Clinical Assays for Human Chorionic Gonadotropin
نویسندگان
چکیده
منابع مشابه
Standardization of assays for human chorionic gonadotropin.
The unsatisfactory standardization of many immunoassays is fairly well recognized, but the problem is hard to tackle (1 ). Recently, studies on the performance of immunoassays for testosterone in female serum (2 ) and for urinary cortisol (1 ) have revealed that the quality of some widely used assays is totally unsatisfactory. The quality of assays for human chorionic gonadotropin (hCG) has als...
متن کاملDiscordant results in human chorionic gonadotropin assays.
Discordance has been reported in human chorionic gonadotropin (hCG) concentrations measured by different immunoassay kits. We examined the results for 40 serum samples assayed with 10 different hCG immunoassay kits. Results varied considerably. Individual sample results varied by as much as 58-fold. Average results for different kits varied by as much as 1.4-fold for pregnancy (20 samples) and ...
متن کاملInappropriate use of commercial human chorionic gonadotropin assays.
I am disappointed that the recent Q&A article in Clinical Chemistry dealing with assays for human chorionic gonadotropin (hCG) did not mention that all commercial hCG assays in the US are FDA cleared only for the early detection of pregnancy (1 ). The current situation is very unsatisfactory, because these assays, with the knowledge of the manufacturers, are in widespread use for oncology. What...
متن کاملClinical assays for human chorionic gonadotropin: what should we measure and how?
Within the last year, human chorionic gonadotropin (hCG) has been a topic of great discussion in both the scientific and popular press. Recent reports have demonstrated that because of hCG’s heterogeneity, assay standardization is an important problem, with different immunoassays giving different results for the same specimens. In addition there have been reports of falsenegative results due to...
متن کاملClinical Assays for Human Chorionic Gonadotropin: What Should We Measure and How?
Within the last year, human chorionic gonadotropin (hCG) has been a topic of great discussion in both the scientific and popular press. Recent reports have demonstrated that because of hCG’s heterogeneity, assay standardization is an important problem, with different immunoassays giving different results for the same specimens. In addition there have been reports of falsenegative results due to...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2009
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2009.133595